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1
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Acknowledgements
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2
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Preliminary
Information
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2.1
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Restrictions
and Disclaimer
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Distribution
Restrictions
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General
Disclaimer
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How
to Reach the Author
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2.2
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Why a
DXM FAQ?
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2.3
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Keeping
DXM Legal
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2.4
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How to
Use This Document
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3
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DXM QuickFAQ
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3.1
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What is
DXM?
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3.2
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You Mean
I Can Get High Off Cough Syrup?
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3.3
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What
Kinds of Cough Medicine are Safe?
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3.4
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What
Happens if I Drink the Wrong Cough Syrup?
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3.5
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I'm
Taking Other Drugs -- Can I Take DXM?
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3.6
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What's
the DXM Trip Like?
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3.7
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How Much
DXM Do I Take?
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3.8
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Is DXM
Like Acid?
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3.9
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Is DXM
Fun?
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3.10
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Is DXM
Dangerous?
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3.11
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If DXM
is Dangerous, Why Do It?
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4
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General Information
About DXM
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4.1
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DXM
Quick Reference Page
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4.2
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What
is Dextromethorphan Hydrobromide (DXM)?
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4.3
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What
is Dextromethorphan Polistirex?
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4.4
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What
is Dextrorphan (DXO)?
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4.5
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Is
DXM Enjoyable as a Recreational Drug?
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4.6
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Is
DXM an Opiate?
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4.7
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Does
Everyone Like DXM?
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4.8
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How
Does One Obtain and Use DXM?
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Cough
Syrups
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Gelcaps
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Tablets
and Capsules (including Coricidin)
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Lozenges
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Pharmaceutical
and Chemical Suppliers
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Extracted
DXM
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Injection
and Other Routes
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4.9
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What
are Some Typical DXM-Containing Preparations?
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4.10
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How
am I Supposed to Drink Cough Syrup?
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4.11
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What
Should I Know About Other Drug Ingredients?
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Decongestants
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Antihistamines
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Guaifenesin
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Analgesics,
Acetaminophen/Paracetamol
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Alcohol
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Food
Coloring and Dyes
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Bromide
Ions
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Other
"Inactive" Ingredients
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4.12
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Why
are So Many DXM Preparations in Liquid Form?
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4.13
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Is
Recreational Use of DXM Illegal?
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4.14
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If
DXM is Legal Why Isn't Everyone Doing It?
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4.15
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New
Medical Uses for DXM
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Diagnostic
Uses
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Neuroprotectant
Uses
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DXM
for Chronic Pain
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DXM
for Drug Addiction
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DXM
for Disease and Miscellaneous Conditions
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4.16
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Drug
Interactions
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Fatal
or Dangerous Interactions
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Beneficial
Drug Interactions
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Recreational
Drug Interactions
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4.17
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General
Warnings
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4.18
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What
About Other Cough Suppressants?
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Noscapine
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Opiates
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Topical
Anaesthetics
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Can
DXM be Detected on Drug Tests?
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5
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The DXM
Experience
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5.1
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What
is the General Character of the DXM
Experience?
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5.2
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Overview
of the Lower Plateaus
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5.3
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The
First Plateau
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Sensory
Effects
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Cognitive/Emotional
Effects
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Motor
Effects
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Memory
Effects
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5.4
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The
Second Plateau
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Sensory
Effects
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Cognitive/Emotional
Effects
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Motor
Effects
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Memory
Effects
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5.5
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The
Transitional Phase
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5.6
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The
Upper Plateaus
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5.7
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The
Third Plateau
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Sensory
Effects
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Cognitive/Emotional
Effects
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Motor
Effects
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Memory
Effects
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5.8
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The
Fourth Plateau
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5.9
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Plateau
Sigma
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5.10
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Is
There Anything Beyond the Fourth Plateau?
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5.11
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What
is the "DXM Third Eye Camera"?
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5.12
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Tussin
Space, Tussin Consciousness
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5.13
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What
is the "Tussin Euphoria" and What Makes it
Unique?
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5.14
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What
Can Happen with Long-term or Regular Use?
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5.15
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Why
does DXM Affect Different People So
Differently?
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5.16
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How
Does DXM Compare With Other Dissociatives?
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6
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DXM Side Effects and
Other Things to Avoid
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6.1
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What
are Some Minor Risks of Occasional Use?
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Nausea
and Other Gastric Disturbances
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Dizziness
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Mild
Allergic Reactions and Histamine Release
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Sexual
Dysfunction
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Diaphoresis
(sweating)
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Impaired
Judgement and Mental Performance
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Hangovers
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Tachycardia
(Increased Heart Rate)
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Pupil
Dilation or Constriction
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Hot
and Cold Flashes
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Facial
Edema
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Mild
Hypertension (High Blood Pressure)
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Mild
Hyperthermia (Increased Temperature)
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Overexertion
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Urticaria
(skin rash/wheal)
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Increased
Bile Secretion
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Inappropriate
Behaviour
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Miscellaneous
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6.2
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What
are Some Major Risks of Occasional Use?
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Panic
Attacks
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Psychotic
Breaks
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Impaired
Judgement in Critical Situations
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Depression
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Serious
Hyperthermia (High Temperature)
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Serious
Hypertension (High Blood Pressure)
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Rhabdomyolysis
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Respiratory
Depression
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Serotonin
Syndrome
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Major
Allergic Reactions and Histamine Release
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Miscellaneous
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6.3
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What
Are the Risks of Regular Use and Binges?
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NMDA
Antagonist Neurotoxicity (Olney's Lesions)
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Cerebral
Hemorrhage and Stroke
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Other
Neurotoxicity Mechanisms
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Mania
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Depression
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Violent
Ideations, Antisocial Behaviour, and Paranoia
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Memory
Impairment
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Language
Impairment
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Weight
Loss
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Loss
of Muscle Control
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Habituation
and Psychological Addiction
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Tolerance
and Physical Addiction
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Psychosis
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Liver,
Kidney, and Pancreas Damage
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Bromide
Poisoning
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Miscellaneous
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Summary:
Regular Use Considered
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6.4
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DXM
and Pregnancy
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6.5
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What
is NMDA Antagonist Neurotoxicity and How do I Prevent
It?
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Overview
and Mechanism of Olney's Lesions
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Dosages
at Which NAN Occurs
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Balancing
the Risks: Is Olney's Research Relevant to DXM
Use?
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A
Look at the Areas Involved
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Preventing
and Limiting NMDA Antagonist Neurotoxicity
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6.6
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Is
DXM Addictive?
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6.7
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Is
DXM Withdrawal Dangerous?
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6.8
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Kicking
the DXM Habit: What to Do If You are Addicted
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Preparing
to Quit
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Quitting
"Cold Turkey"
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Build-Down
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After
Quitting: When Can I Use DXM Again?
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6.9
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DXM
Hangovers -- Avoiding and Alleviating
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6.10
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How
Toxic is DXM, and What is the Lethal Dose?
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6.11
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Do
You Recommend DXM for Recreational Use?
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6.12
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Help!
What do I do if ...
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Itching
(the "Robo Itch")
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Fast
Heartbeat
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Panic
Attacks
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Irregular
or Skipped Heartbeats
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Nausea,
Vomiting, Gas, and Diarrhea
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Unconsciousness
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Overdose
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High
Temperature / Fever
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Shortness
of Breath / Breathing Problems
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Choking
On Your Tongue
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Nosebleeds
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Feeling
"dead" / losing one's body
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Hangovers
(lethargy and feeling "not all there")
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Prolonged
Dissociation From the Real World
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Serotonin
Syndrome
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Bad
Trips
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Psychotic
Breaks
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6.13
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How
to Know When You've Done Too Much DXM
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7
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Getting the Most Out of
DXM
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7.1
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General
Tips on Enjoying the DXM Experience
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7.2
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What are
Some Fun or Interesting Things to Do on DXM?
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Listen
to Music
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7.3
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Watch a
Movie
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Make
Music
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Dance
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Swimming
(First Plateau Only!)
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Group
Tripping
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Paranormal/Spiritual
Exploration
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Observe
People
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7.4
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What
Tools Can Enhance the DXM Experience?
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Sensory
Deprivation
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Ganzfeld
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Light
and Sound (Brainwave) Machines
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Hemisphere
Synch Audio Tapes
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Trip
Programs
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Trip
Toys
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7.5
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What are
Some Things to Avoid on DXM?
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Heavy
Exercise
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Driving
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Going
to Class, School, or Work on DXM
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Dose
"Boosting" and Re-dosing
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Stressful
Environments
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7.6
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What is
the "50 Trip Limit" and How Can I Avoid It?
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7.7
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Why Can't
I Hallucinate on DXM?
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8
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Altered States and
Paranormal Experiences
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8.1
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Preliminary
Information and Discussion
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8.2
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What
Paranormal and Altered State Experiences Occur on
DXM?
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The
Dissociative Spiral
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Deja
Vu and Other Memory Mishaps
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Out-of-Body
Experiences (OOBEs)
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Near-Death
and Rebirth Experiences
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Contact
with Alien and Spiritual Beings
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Clairvoyance,
ESP, and Other Psi Phenomena
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Memory
Loops and Prescient Sensations
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Dissociative
Thought Patterns
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8.3
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Cosmic
Coincidence Central and the Alien Conspiracy
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8.4
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Are
These Experiences Dangerous?
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8.5
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How
Can These Be Explained
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Temporal
Anomalies
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Complex
Partial Seizures
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Influence
of the Unseen Environment
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Spiritual
Explanations
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8.6
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How
do I Maximize Altered States and Paranormal
Experiences?
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Theta
Stimulation
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Hemisphere
Synch Tapes
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Magnetic
Stimulation
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Sensory
Deprivation and Ganzfeld
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Predosing
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Meditation
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8.7
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Factors
Affecting Susceptibility to Paranormal
Experiences
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8.8
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A
Warning About "Spiritual Shortcuts"
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8.9
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A
Warning About Temporal Lobe Epilepsy
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9
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Physiological
Effects of DXM
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9.1
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How
Does DXM Inhibit the Cough Reflex?
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9.2
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How
Does DXM Cause its Psychoactive Effects?
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General
Information
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Contribution
of the PCP2 Binding Site
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Contribution
of the Sigma Binding Sites
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Contribution
of the NMDA Receptor
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Temporal
Lobe Involvement
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Contributions
of Indirect Activity
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Flanging
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Hyper-Abstraction
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Delusions
and Memory Problems
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9.3
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Why
Does DXM Exhibit Plateaus?
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Plateaus
1-3: Multiple Receptors
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The
Fourth Plateau: Sensory Shutdown
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9.4
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Why
is This So Complicated?
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9.5
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Pharmacokinetics:
How DXM is Metabolized
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Factors
Affecting Metabolism of DXM
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10
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Neuropharmacology of
DXM
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10.1
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What
is a Receptor, Anyway? (Basic
Neuropharmacology)
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The
Structure of a Nerve Cell
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Neurotransmission
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10.2
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What
are Sigma Receptors?
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Sigma
1 Receptors and General Sigma Information
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Sigma
2 Receptors
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Sigma
3 Receptors
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10.3
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What
Are NMDA Receptors?
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NMDA
and Other Glutamate Receptors
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NMDA
Receptor Structure and Function
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NMDA
Receptors and Excitotoxicity
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10.4
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What
are PCP2 Receptors?
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10.5
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What
are Na+ and Ca2+
Channels?
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10.6
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How
Does DXM Compare to Other Dissociatives at These
Receptors?
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10.7
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Endopsychosin
and the Big Picture
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11
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DXM Chemistry and
Extraction
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11.1
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How
Can I Extract DXM From Cough Syrups and
Gelcaps?
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Theory
of Acid-Base Extractions
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Single-Phase
Acid-Base Extraction of DXM
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Agent
Lemon: Dual-Phase Acid-Base Extraction of DXM
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Precipitation
Method
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11.2
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How
Can I Get Rid of Other Drug Ingredients?
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Acetaminophen
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Guaifenesin
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Antihistamines
and Decongestants
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11.3
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How
Can I Test for Acetaminophen?
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11.4
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How
do I Use Free Base DXM?
|
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11.5
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How
Can I Synthesize DXM?
|
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11.6
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What
Can I Synthesize From DXM?
|
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Dextrorphan
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Levorphanol
/ Levomethorphan
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3-Substituted
Analogs
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12
|
DXM Drug
Culture
|
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12.1
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Is
There, or Was There, a DXM Drug Culture?
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DXM
in the 1960's
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DXM
in the 1970's
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DXM
in the 1980's
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DXM
in the 1990's
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The
Future of DXM Use
|
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12.2
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Why
Haven't I Heard About DXM Drug Culture?
|
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12.3
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DXM
"Drug Slang"
|
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Non-American
DXM Drug Slang
|
|
12.4
|
How
do I Tell My Friends I'm Getting High off Cough
Syrup?
|
|
|
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|
13
|
Mixing DXM and Other
Drugs
|
|
13.1
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Alcohol
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13.2
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Barbiturates
and Benzodiazepines
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13.3
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Amphetamines
and Other Psychostimulants
|
|
13.4
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Cannabis
(Marijuana)
|
|
13.5
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LSD,
Psilocybin (Shrooms), and Other 5HT
Hallucinogens
|
|
13.6
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Opiates
|
|
13.7
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PCP
and Ketamine
|
|
13.8
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Nicotine
|
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13.9
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Phenethylamines
(MDMA, MDA, 2CB, etc)
|
|
13.10
|
Nootropics
(Smart Drugs)
|
|
13.11
|
Miscellaneous
Other Drugs
|
|
|
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|
14
|
DXM Experiences
and Personal Reports
|
|
14.1
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First
and Second Plateau Experiences
|
|
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Positive
Experiences
|
|
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Negative
Experiences
|
|
14.2
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Third
and Fourth Plateau Experiences
|
|
|
Positive
Experiences
|
|
|
Negative
Experiences
|
|
14.3
|
Long
Term Use Experiences
|
|
|
Positive
Experiences
|
|
|
Negative
Experiences
|
|
14.4
|
Multiple
Drug Experiences
|
|
|
DXM
+ Cannabis + Alcohol + Opium
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|
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DXM
+ Cyclazine
|
|
|
DXM
+ Mushrooms + LSD + Cannabis + Nitrous Oxide
|
|
|
|
|
15
|
Appendices
|
|
15.1
|
Appendix
1: P450 Inhibiting Drugs
|
|
15.2
|
Appendix
2: Neuropharmacology of Recreational Drugs
|
|
15.3
|
Appendix
3: Other Sigma and NMDA Ligands
|
|
|
|
|
16
|
Glossary
|
|
|
|
|
17
|
References
|